Effective Index: a formal measure of drug effects

Dematte', Lorenzo and Prandi, Davide and Priami, Corrado and Romanel, Alessandro (2007) Effective Index: a formal measure of drug effects. UNSPECIFIED. (Unpublished)

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    Abstract

    This paper proposes the Effective Index, a formal tool to support decision processes in drug discovery. The Effective Index is based on concurrency theory and process calculi to describe incrementally complex biological systems and on Markov process theory to handle quantitative information. A running case study concerning the pathways and the drugs related to hypertension exploits the approach.

    Item Type: Departmental Technical Report
    Department or Research center: CoSBi (Center for Computational and Systems Biology)
    Subjects: Q Science > QA Mathematics > QA076 Computer software > QA076.7 Programming Languages - Semantics
    Report Number: TR-05-2007
    Repository staff approval on: 01 Dec 2009

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