Dematte', Lorenzo and Prandi, Davide and Priami, Corrado and Romanel, Alessandro (2007) Effective Index: a formal measure of drug effects. UNSPECIFIED. (Unpublished)
Abstract
This paper proposes the Effective Index, a formal tool to support decision processes in drug discovery. The Effective Index is based on concurrency theory and process calculi to describe incrementally complex biological systems and on Markov process theory to handle quantitative information. A running case study concerning the pathways and the drugs related to hypertension exploits the approach.
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